Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | NGLY1 | Q96IV0 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7432725 | 0.82 | KDM4E (0.57) | KDM4EMAPTALDH1A1HSD17B10AKR1C3 | |
| SCHEMBL7434442 | 0.82 | KDM4E (0.58) | KDM4EMAPTALDH1A1HCAR2MEN1 | |
| SCHEMBL7433961 | 0.82 | ABCC1 (0.47) | PTPN1ABCC1KDM4EMAPTHPGD | |
| SCHEMBL7436413 | 0.79 | SELP (0.46) | ALDH1A1HCAR2MEN1KMT2ALMNA | |
| SCHEMBL7425861 | 0.79 | SELP (0.60) | KDM4EALDH1A1HSD17B10HCAR2MEN1 | |
| SCHEMBL22022881 | 0.78 | HCAR2 (0.65) | HCAR2 | |
| SCHEMBL14398972 | 0.77 | PTPN1 (0.59) | PTPN1ABCC1KDM4EMAPTHPGD | |
| SCHEMBL2841346 | 0.76 | PTPN1 (0.66) | PTPN1ABCC1KDM4EMAPTHPGD | |
| SCHEMBL7438717 | 0.76 | ALOX15 (0.50) | HCAR2GAA | |
| SCHEMBL22022900 | 0.76 | HCAR2 (0.59) | PTPN1AKR1C3AKR1C2HCAR2KDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |