SCHEMBL7438458

SCHEMBL7438458

CCC(CC)(CCC=NO)C(=O)OC

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.36
CYP4A11 Q02928 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7436601 0.81 CYP4F2 (0.38) CYP4F2CYP4A11
SCHEMBL17617116 0.76 CYP4F2 (0.42) CYP4F2CYP4A11
SCHEMBL2477744 0.75 CYP4F2 (0.39) CYP4F2CYP4A11
SCHEMBL2204111 0.73 CYP4F2 (0.39) CYP4F2CYP4A11
SCHEMBL5000217 0.73 CYP4F2 (0.39) CYP4F2CYP4A11
SCHEMBL28936386 0.72 CYP4F2 (0.48) CYP4F2CYP4A11
SCHEMBL26828304 0.72 CYP4F2 (0.40) CYP4F2CYP4A11
SCHEMBL28718243 0.71 CYP4F2 (0.38) CYP4F2CYP4A11
SCHEMBL18597562 0.71 CYP4F2 (0.39) CYP4F2CYP4A11
SCHEMBL7438044 0.71 CYP4F2 (0.67) CYP4F2CYP4A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6066666-A OPTIONALLY N-SUBSTITUTED 3-MONO- AND DI-SUBSTITUTED 2-PYRROLIDINONES AND THIOLACTAM ANALOGS; TREAT SEIZURES, ANXIETY, AND ENHANCING 4-AMINOBUTYRIC ACID (GABA)-INDUCED CHLORIDE CURRENTS AT GABA RECEPTOR/IONOPHORE COMPLEX WASHINGTON UNIVERSITY (US) 2000-05-23 US disclosed
US-5776959-A Anticonvulsant and anxiolytic lactam and thiolactam derivatives WASHINGTON UNIVERSITY (US) 1998-07-07 US disclosed