Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 15/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7433639 | 0.87 | ITGB3 (0.49) | ITGB3ITGA2B | |
| SCHEMBL6949949 | 0.81 | ITGB3 (0.47) | ITGB3ITGA2B | |
| SCHEMBL7442287 | 0.79 | ITGB3 (0.45) | ITGB3ITGA2B | |
| SCHEMBL7438453 | 0.78 | ITGB3 (0.59) | ITGB3ITGA2BL3MBTL1HDAC1 | |
| SCHEMBL7438459 | 0.78 | ITGB3 (0.59) | ITGB3ITGA2BL3MBTL1HDAC1 | |
| SCHEMBL7397564 | 0.75 | ITGB3 (0.47) | ITGB3ITGA2B | |
| SCHEMBL7397566 | 0.75 | ITGB3 (0.47) | ITGB3ITGA2B | |
| SCHEMBL7338319 | 0.71 | PARP1 (0.44) | ITGB3ITGA2B | |
| SCHEMBL6949734 | 0.71 | ITGB3 (0.73) | ITGB3ITGA2B | |
| SCHEMBL6949739 | 0.71 | ITGB3 (0.73) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403578-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | SMITHKLINE BEECHAM CORPORATION | 2002-06-11 | — | — | US | disclosed |
| EP-0674623-A1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014776-A2 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-07-07 | — | — | WO | disclosed |