Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.38 |
| ▸ | MEN1 | O00255 | 7/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7439730 | 0.92 | ALDH1A1 (0.39) | KMT2AMEN1HPGDALDH1A1TSHR | |
| SCHEMBL7440109 | 0.92 | ALDH1A1 (0.39) | KMT2AMEN1HPGDALDH1A1TSHR | |
| SCHEMBL7444290 | 0.92 | ALDH1A1 (0.39) | KMT2AMEN1HPGDALDH1A1TSHR | |
| SCHEMBL7446583 | 0.89 | KMT2A (0.40) | KMT2AMEN1PTPN2PTPN1PTPN6 | |
| SCHEMBL7452040 | 0.85 | ALDH1A1 (0.39) | KMT2AMEN1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7439743 | 0.84 | MEN1 (0.37) | KMT2AMEN1HPGDALDH1A1MAPT | |
| SCHEMBL7437038 | 0.83 | MEN1 (0.36) | KMT2AMEN1HPGDALDH1A1MAPT | |
| SCHEMBL7438522 | 0.83 | GAA (0.40) | KMT2AMEN1PTPN2PTPN1PTPN6 | |
| SCHEMBL7459675 | 0.83 | MEN1 (0.37) | KMT2AMEN1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7438518 | 0.81 | KMT2A (0.38) | KMT2AMEN1PTPN2PTPN1PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384028-B1 | TREATMENT OF CARDIOVASCULAR DISORDERS, ANTICOAGULANTS AND VALVE REPLACEMENT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |
| WO-1996029309-A1 | N-ACYLPIPERIDINYLCARBONYLAMINOCARBOXYLIC ACIDS AND THEIR USE AS GLYCOPROTEIN IIB/IIa ANTAGONISTS AND FIBRINOGEN-BLOOD PLATELETS BINDING INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-09-26 | — | — | WO | disclosed |