Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 15/20 | 0.56 |
| ▸ | ITGAV | P06756 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7438528 | 1.00 | ITGB3 (0.56) | ITGB3ITGA2BITGAVALDH1A1LMNA | |
| SCHEMBL7399596 | 0.91 | ITGB3 (0.68) | ITGB3ITGA2BITGAV | |
| SCHEMBL7397591 | 0.91 | ITGB3 (0.68) | ITGB3ITGA2BITGAV | |
| SCHEMBL7399604 | 0.88 | ITGB3 (0.52) | ITGB3ITGA2BITGAVALDH1A1LMNA | |
| SCHEMBL7395726 | 0.86 | ITGB3 (0.69) | ITGB3ITGA2BITGAV | |
| SCHEMBL7595687 | 0.86 | ITGB3 (0.69) | ITGB3ITGA2BITGAV | |
| SCHEMBL7432285 | 0.85 | ITGB3 (0.48) | ITGB3ITGA2BITGAVHDAC6HDAC1 | |
| SCHEMBL7432277 | 0.85 | ITGB3 (0.48) | ITGB3ITGA2BITGAVHDAC6HDAC1 | |
| SCHEMBL7595704 | 0.83 | ITGB3 (0.54) | ITGB3ITGA2BITGAVSMN1; SMN2HDAC6 | |
| SCHEMBL7402539 | 0.82 | ITGB3 (0.59) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674623-A1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-10-04 | — | — | EP | claimed |
| WO-1994014776-A2 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-07-07 | — | — | WO | claimed |
| US-6403578-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | SMITHKLINE BEECHAM CORPORATION | 2002-06-11 | — | — | US | disclosed |
| EP-0674623-A1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014776-A2 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-07-07 | — | — | WO | disclosed |