Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7438673 | 0.91 | ITGB3 (0.52) | KDM4EALDH1A1CYP2C9CYP2C19MEN1 | |
| Hydrogen Sulfide SCHEMBL7442224 | 0.80 | NPY2R (0.50) | KDM4EALDH1A1CYP2C9CYP2C19MEN1 | |
| SCHEMBL7435911 | 0.79 | ITGB3 (0.57) | KDM4EALDH1A1CYP2C9CYP2C19MEN1 | |
| Trifluoroacetic Acid SCHEMBL7448252 | 0.77 | ITGB3 (0.52) | KDM4EALDH1A1CYP2C9CYP2C19MEN1 | |
| SCHEMBL7443543 | 0.77 | MEN1 (0.40) | KDM4EALDH1A1CYP2C9CYP2C19MEN1 | |
| SCHEMBL7337291 | 0.75 | ITGB3 (0.56) | KDM4EALDH1A1CYP2C9CYP2C19MEN1 | |
| SCHEMBL7336222 | 0.75 | ITGB3 (0.46) | KDM4EALDH1A1CYP2C9CYP2C19MEN1 | |
| SCHEMBL7449755 | 0.75 | ITGB3 (0.52) | KDM4ECYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL7436177 | 0.74 | ITGB3 (0.51) | KDM4EALDH1A1CYP2C9CYP2C19MEN1 | |
| SCHEMBL7437197 | 0.73 | ITGB3 (0.41) | KDM4EALDH1A1CYP2C9CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623120-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993014077-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |