Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.30 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.30 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29636861 | 0.77 | CDK1 (0.49) | KDM4EALDH1A1SMN1; SMN2CDK1FGFR1 | |
| SCHEMBL602131 | 0.77 | CDK1 (0.49) | KDM4EALDH1A1SMN1; SMN2CDK1FGFR1 | |
| SCHEMBL24682199 | 0.74 | PI4KA (0.39) | KDM4EALDH1A1SMN1; SMN2CDK1FGFR1 | |
| SCHEMBL5839419 | 0.73 | FGFR1 (0.40) | KDM4EALDH1A1CDK1FGFR1FGFR4 | |
| SCHEMBL1371020 | 0.72 | FDPS (0.40) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL29141665 | 0.70 | ADORA2A (0.41) | KDM4EALDH1A1CDK1FGFR1FGFR4 | |
| SCHEMBL27773226 | 0.69 | POLB (0.44) | KDM4EALDH1A1FGFR1FGFR4 | |
| SCHEMBL111660 | 0.69 | KDM4E (0.36) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4194084 | 0.69 | CCNA2 (0.32) | CDK1FGFR1FGFR4MET | |
| SCHEMBL27538550 | 0.69 | ADORA2A (0.44) | KDM4EALDH1A1SMN1; SMN2CDK1FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430036-A1 | SUBSTITUTED 6-(BENZYLAMINO) PURINE RIBOSIDE DERIVATIVES, USE THEREOF AND COMPOSITIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010130233-A1 | SUBSTITUTED 6-(BENZYLAMINO) PURINE RIBOSIDE DERIVATIVES, USE THEREOF AND COMPOSITIONS CONTAINING THESE DERIVATIVES | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2010-11-18 | — | — | WO | disclosed |