Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 3/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442260 | 0.91 | CYP2C19 (0.55) | MMP8EPHX2NPC1RAB9AEPHX1 | |
| SCHEMBL13066397 | 0.85 | MMP8 (0.55) | MMP8EPHX2L3MBTL1NPC1HPGD | |
| SCHEMBL28863035 | 0.84 | EPHX1 (0.56) | MMP8L3MBTL1NPC1HPGDRAB9A | |
| SCHEMBL8083610 | 0.84 | MMP8 (0.54) | MMP8EPHX2L3MBTL1NPC1HPGD | |
| SCHEMBL1403819 | 0.82 | EPHX2 (0.55) | MMP8EPHX2L3MBTL1NPC1HPGD | |
| SCHEMBL7435493 | 0.81 | MMP8 (0.57) | MMP8L3MBTL1HPGDEPHX1KMT2A | |
| SCHEMBL10706967 | 0.81 | EPHX2 (0.54) | MMP8EPHX2L3MBTL1NPC1HPGD | |
| SCHEMBL8083494 | 0.81 | MMP8 (0.50) | MMP8EPHX2L3MBTL1EPHX1KDM4E | |
| SCHEMBL7436079 | 0.81 | KDM4E (0.53) | NPC1RAB9AGAAKDM4ECYP2D6 | |
| SCHEMBL14491525 | 0.80 | SMN1; SMN2 (0.68) | MMP8EPHX2L3MBTL1NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814622-A | COMPOUND USEFUL AS TRYPSIN LIKE SERINE PROTEASE AS THROMBIN INHIBITORS | ADIR ET COMPAGNIE (FR) | 1998-09-29 | — | — | US | disclosed |