Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SELP | P16109 | 1/20 | 0.41 |
| ▸ | SELE | P16581 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7424621 | 0.91 | ALDH1A1 (0.41) | ALDH1A1NPC1RAB9ACYP2C9KDM4E | |
| SCHEMBL7393353 | 0.90 | KMT2A (0.50) | ALDH1A1RAB9ACYP2C9KDM4EMAPT | |
| SCHEMBL7430329 | 0.89 | CYP2C9 (0.51) | ALDH1A1NPC1RAB9ACYP2C9KDM4E | |
| SCHEMBL7432759 | 0.88 | ALDH1A1 (0.48) | ALDH1A1NPC1RAB9ACYP2C9KDM4E | |
| SCHEMBL7437062 | 0.87 | ALDH1A1 (0.47) | ALDH1A1NPC1RAB9ACYP2C9KDM4E | |
| SCHEMBL7429403 | 0.87 | ALDH1A1 (0.47) | ALDH1A1NPC1RAB9ACYP2C9KDM4E | |
| SCHEMBL7432768 | 0.87 | ALDH1A1 (0.52) | ALDH1A1NPC1RAB9ACYP2C9KDM4E | |
| SCHEMBL7435480 | 0.87 | NPC1 (0.56) | ALDH1A1NPC1RAB9ACYP2C9KDM4E | |
| SCHEMBL7429657 | 0.86 | ALDH1A1 (0.46) | ALDH1A1NPC1RAB9ACYP2C9KDM4E | |
| SCHEMBL7433885 | 0.86 | ALDH1A1 (0.46) | ALDH1A1NPC1RAB9ACYP2C9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210266-A | Analgesic enkephalinase inhibitors | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1993-05-11 | — | — | US | disclosed |
| US-5179125-A | Analgesics | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1993-01-12 | — | — | US | disclosed |
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |