Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7438933 | 1.00 | NAMPT (0.45) | NAMPTGPR119MAPK1PRMT5WDR77 | |
| SCHEMBL7450160 | 0.91 | NAMPT (0.46) | NAMPTGPR119MAPK1PRMT5WDR77 | |
| SCHEMBL7450170 | 0.91 | NAMPT (0.46) | NAMPTGPR119MAPK1PRMT5WDR77 | |
| SCHEMBL30771260 | 0.83 | NAMPT (0.52) | NAMPTGPR119MAPK1PRMT5WDR77 | |
| SCHEMBL3703899 | 0.83 | NAMPT (0.52) | NAMPTGPR119MAPK1PRMT5WDR77 | |
| SCHEMBL1791197 | 0.77 | GPR119 (0.46) | NAMPTGPR119MAPK1PRMT5WDR77 | |
| SCHEMBL4237414 | 0.74 | KDM4E (0.56) | GPR119KDM4EPKMMEN1KMT2A | |
| SCHEMBL4237418 | 0.74 | KDM4E (0.56) | GPR119KDM4EPKMMEN1KMT2A | |
| SCHEMBL20015682 | 0.74 | GPR119 (0.57) | GPR119KDM4EPKMMEN1KMT2A | |
| SCHEMBL20015272 | 0.74 | GPR119 (0.57) | GPR119KDM4EPKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384028-B1 | TREATMENT OF CARDIOVASCULAR DISORDERS, ANTICOAGULANTS AND VALVE REPLACEMENT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |
| EP-0869944-A1 | N-ACYLPIPERIDINYLCARBONYLAMINOCARBOXYLIC ACIDS AND THEIR USE AS GLYCOPROTEIN IIB/IIa ANTAGONISTS AND FIBRINOGEN-BLOOD PLATELETS BINDING INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-14 | — | — | EP | disclosed |
| WO-1996029309-A1 | N-ACYLPIPERIDINYLCARBONYLAMINOCARBOXYLIC ACIDS AND THEIR USE AS GLYCOPROTEIN IIB/IIa ANTAGONISTS AND FIBRINOGEN-BLOOD PLATELETS BINDING INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-09-26 | — | — | WO | disclosed |