Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KCNA4 | P22459 | 1/20 | 0.32 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.32 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.31 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.31 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.31 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.30 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7438962 | 1.00 | HTR2A (0.41) | HTR2AHTR2CHTR2BABCB1PTGS2 | |
| SCHEMBL9381070 | 0.75 | HTR2A (0.66) | HTR2AHTR2CHTR2BABCB1PTGS2 | |
| SCHEMBL16841701 | 0.75 | ABCB1 (0.43) | HTR2AHTR2CHTR2BABCB1PTGS2 | |
| SCHEMBL7976048 | 0.75 | HTR2A (0.41) | HTR2AHTR2CHTR2BABCB1PTGS2 | |
| SCHEMBL15557343 | 0.75 | ABCB1 (0.43) | HTR2AHTR2CHTR2BABCB1PTGS2 | |
| SCHEMBL7976045 | 0.75 | HTR2A (0.41) | HTR2AHTR2CHTR2BABCB1PTGS2 | |
| SCHEMBL7976044 | 0.75 | HTR2A (0.41) | HTR2AHTR2CHTR2BABCB1PTGS2 | |
| SCHEMBL9381065 | 0.75 | HTR2A (0.66) | HTR2AHTR2CHTR2BABCB1PTGS2 | |
| SCHEMBL9381062 | 0.75 | HTR2A (0.66) | HTR2AHTR2CHTR2BABCB1PTGS2 | |
| SCHEMBL8845602 | 0.74 | HTR2C (0.41) | HTR2AHTR2CHTR2BABCB1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992000972-A1 | RENIN INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1992-01-23 | — | — | WO | disclosed |