Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14305176 | 0.77 | HDAC3 (0.56) | MEN1KMT2APOLBGAAHSD17B10 | |
| SCHEMBL14198603 | 0.70 | KMT2A (0.79) | MEN1KMT2APOLBGAASMN1; SMN2 | |
| SCHEMBL15923755 | 0.69 | RAB9A (0.62) | HSD17B10SMN1; SMN2MAPTL3MBTL1TSHR | |
| SCHEMBL7439075 | 0.69 | KMT2A (0.44) | MEN1KMT2APOLBTP53MAPT | |
| SCHEMBL4906852 | 0.69 | MEN1 (0.58) | MEN1KMT2APOLBHSD17B10SMN1; SMN2 | |
| SCHEMBL10561030 | 0.69 | POLB (0.55) | MEN1KMT2APOLBGAASMN1; SMN2 | |
| SCHEMBL9312776 | 0.68 | GAA (0.84) | MEN1KMT2APOLBGAASMN1; SMN2 | |
| SCHEMBL7837431 | 0.68 | HDAC8 (0.77) | MEN1KMT2APOLBGAAMAPT | |
| SCHEMBL9134606 | 0.68 | SMN1; SMN2 (0.72) | MEN1KMT2APOLBSMN1; SMN2MAPT | |
| SCHEMBL9798486 | 0.68 | HPGD (0.63) | MEN1KMT2APOLBGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706521-A1 | NOVEL IMIDES | CELGENE CORPORATION (US) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995001348-A2 | IMIDES AS INHIBITORS OF TNP ALPHA | CELGENE CORPORATION (US) | 1995-01-12 | — | — | WO | disclosed |