Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.54 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4985262 | 0.95 | EPHX1 (0.60) | EPHX1HTTALDH1A1ERCC1ERCC4 | |
| SCHEMBL2941854 | 0.83 | EPHX1 (0.58) | EPHX1HTTALDH1A1HPGDNAAA | |
| SCHEMBL4908547 | 0.82 | ERCC1 (0.54) | HTTALDH1A1ERCC1ERCC4PKM | |
| SCHEMBL29623875 | 0.81 | CA12 (0.53) | — | |
| SCHEMBL7294555 | 0.81 | ERCC1 (0.57) | ALDH1A1ERCC1ERCC4PKMITGB3 | |
| SCHEMBL17117275 | 0.81 | TRPV1 (0.65) | EPHX1ALDH1A1ERCC1ERCC4TSHR | |
| SCHEMBL8269680 | 0.79 | HPGD (0.55) | HTTALDH1A1HPGD | |
| SCHEMBL14219224 | 0.79 | NAAA (0.69) | HTTTSHRHPGDNAAA | |
| SCHEMBL13073724 | 0.78 | ERCC1 (0.71) | EPHX1ERCC1ERCC4HPGD | |
| SCHEMBL8269695 | 0.78 | EPHX2 (0.59) | EPHX1HTTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998022494-A9 | METHODS AND COMPOUNDS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR SYNTHESIS | — | 1998-08-20 | — | — | WO | disclosed |