Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.68 |
| ▸ | HTR2C | P28335 | 1/20 | 0.68 |
| ▸ | MPO | P05164 | 13/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.58 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.58 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7431917 | 1.00 | HTR2A (0.68) | HTR2AHTR2CMPOSLC6A4GPR84 | |
| SCHEMBL11442600 | 0.89 | GPR84 (0.58) | HTR2AHTR2CMPOSLC6A4GPR84 | |
| SCHEMBL18647216 | 0.89 | GPR84 (0.58) | HTR2AHTR2CMPOSLC6A4GPR84 | |
| SCHEMBL11440763 | 0.89 | GPR84 (0.58) | HTR2AHTR2CMPOSLC6A4GPR84 | |
| SCHEMBL19047013 | 0.83 | HTR2C (0.68) | HTR2AHTR2CSLC6A4HTR1AKMT2A | |
| SCHEMBL5791670 | 0.83 | HTR2A (0.68) | HTR2AHTR2CMPOSLC6A4GPR84 | |
| SCHEMBL7429865 | 0.83 | GPR84 (0.58) | HTR2AHTR2CSLC6A4GPR84TRPM8 | |
| SCHEMBL22796513 | 0.83 | HTR2A (0.56) | HTR2AHTR2CSLC6A4HTR1AKMT2A | |
| SCHEMBL7426732 | 0.83 | HTR2A (0.56) | HTR2AHTR2CSLC6A4HTR1AKMT2A | |
| SCHEMBL9526444 | 0.83 | HTR2C (0.68) | HTR2AHTR2CSLC6A4HTR1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5140009-A | Stable against proteolytic enzymes; anticarcinogenic agents; urogenital disorders | TAP PHARMACEUTICALS, INC. (US) | 1992-08-18 | — | — | US | claimed |
| EP-0127899-B1 | CYCLIC PENTAPEPTIDES DISPLAYING SOMATOSTATIN ANTAGONISM AND METHOD OF TREATMENT OF MAMMALS THEREWITH | The Administrators of The Tulane University Educational Fund (US) | 1987-10-21 | — | — | EP | claimed |
| EP-0188214-A2 | Novel growth hormone-releasing peptides and method of treating mammals therewith | The Administrators of The Tulane University Educational Fund (US) | 1986-07-23 | — | — | EP | claimed |
| EP-0145768-A1 | CYCLIC PENTAPEPTIDES DISPLAYING SOMATOSTATIN ANTAGONISM AND METHOD OF TREATMENT OF MAMMALS THEREWITH | COY, David Howard (US) | 1985-06-26 | — | — | EP | claimed |
| WO-1984004916-A1 | CYCLIC PENTAPEPTIDES DISPLAYING SOMATOSTATIN ANTAGONISM AND METHOD OF TREATMENT OF MAMMALS THEREWITH | COY DAVID HOWARD (US) | 1984-12-20 | — | — | WO | claimed |
| EP-0127899-A1 | Cyclic pentapeptides displaying somatostatin antagonism and method of treatment of mammals therewith | The Administrators of The Tulane University Educational Fund (US) | 1984-12-12 | — | — | EP | claimed |
| US-5416073-A | Replacements and derivatives of terminal amino acid residues increased milk production in cows | THE ADMINSTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 1995-05-16 | — | — | US | disclosed |
| EP-0127899-B1 | CYCLIC PENTAPEPTIDES DISPLAYING SOMATOSTATIN ANTAGONISM AND METHOD OF TREATMENT OF MAMMALS THEREWITH | The Administrators of The Tulane University Educational Fund (US) | 1987-10-21 | — | — | EP | disclosed |
| EP-0188214-A2 | Novel growth hormone-releasing peptides and method of treating mammals therewith | The Administrators of The Tulane University Educational Fund (US) | 1986-07-23 | — | — | EP | disclosed |
| EP-0145768-A1 | CYCLIC PENTAPEPTIDES DISPLAYING SOMATOSTATIN ANTAGONISM AND METHOD OF TREATMENT OF MAMMALS THEREWITH | COY, David Howard (US) | 1985-06-26 | — | — | EP | disclosed |
| EP-0136475-A2 | Novel growth hormone-releasing peptides and method of treating mammals therewith | The Administrators of The Tulane University Educational Fund (US) | 1985-04-10 | — | — | EP | disclosed |
| US-4505897-A | INCREASING RELEASE OF GROWTH HORMONE, INSULIN, AND GLUCAGON | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 1985-03-19 | — | — | US | disclosed |
| WO-1984004916-A1 | CYCLIC PENTAPEPTIDES DISPLAYING SOMATOSTATIN ANTAGONISM AND METHOD OF TREATMENT OF MAMMALS THEREWITH | COY DAVID HOWARD (US) | 1984-12-20 | — | — | WO | disclosed |
| EP-0127899-A1 | Cyclic pentapeptides displaying somatostatin antagonism and method of treatment of mammals therewith | The Administrators of The Tulane University Educational Fund (US) | 1984-12-12 | — | — | EP | disclosed |
| EP-0023192-B1 | CYCLOPEPTIDES AND PHARMACEUTICAL PREPARATIONS THEREOF, PROCESS FOR THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1984-03-28 | — | — | EP | disclosed |
| US-4328214-A | OCTAPEPTIDES, ANTIDIABETICS, TREATING BLOOD LOSSES IN GASTROINTESTINAL TRACT | CIBA-GEIGY CORPORATION (US) | 1982-05-04 | — | — | US | disclosed |
| US-4224199-A | ANTIDIABETIC | MEYERS CHESTER A | 1980-09-23 | — | — | US | disclosed |