SCHEMBL7439232

SCHEMBL7439232

O=C(O)CN1C(=O)N(C(CS)Cc2ccccc2)C(=O)C1Cc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PLA2G10 O15496 1/20 0.39
PLA2G5 P39877 1/20 0.39
HDAC6 Q9UBN7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7441022 0.90 MEN1 (0.44)
SCHEMBL7443198 0.83
SCHEMBL7436233 0.82 MME (0.39)
SCHEMBL7434083 0.81 MME (0.38)
SCHEMBL7435792 0.81 MME (0.37)
SCHEMBL7433463 0.80 MME (0.37)
SCHEMBL7440453 0.80 MME (0.44)
SCHEMBL7445173 0.80 POLB (0.36)
SCHEMBL7443934 0.79 GAA (0.36)
SCHEMBL7439237 0.79 ACE (0.41) PLA2G10PLA2G5HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0640594-A1 Hydantoin derivative as metalloprotease inhibitor FUJIREBIO INC. (JP) 1995-03-01 EP disclosed