Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.39 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7441031 | 0.90 | SSTR5 (0.46) | — | |
| SCHEMBL7433475 | 0.85 | SIGMAR1 (0.44) | ACE | |
| SCHEMBL7443207 | 0.83 | ACE (0.41) | ACE | |
| SCHEMBL7436241 | 0.82 | ACE (0.42) | ACE | |
| SCHEMBL7435799 | 0.81 | ACE (0.39) | ACE | |
| SCHEMBL7434091 | 0.81 | ACE (0.41) | ACE | |
| SCHEMBL7445183 | 0.80 | ACE (0.38) | ACE | |
| SCHEMBL7440462 | 0.80 | ACE (0.45) | ACE | |
| SCHEMBL7439232 | 0.79 | PLA2G10 (0.39) | HDAC6PLA2G10PLA2G5 | |
| SCHEMBL7441067 | 0.76 | CYP3A4 (0.44) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |