⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1385711 | 0.97 | — | — | |
| Ammonia Solution, Strong SCHEMBL11373086 | 0.95 | — | — | |
| SCHEMBL11045176 | 0.95 | — | — | |
| SCHEMBL16415744 | 0.95 | — | — | |
| SCHEMBL9561374 | 0.95 | — | — | |
| SCHEMBL6695619 | 0.75 | CYP3A4 (0.38) | — | |
| SCHEMBL19180222 | 0.74 | ALDH1A1 (0.45) | — | |
| SCHEMBL9857347 | 0.74 | — | — | |
| SCHEMBL1076725 | 0.72 | — | — | |
| SCHEMBL4434220 | 0.71 | CYP3A4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110229284-B | Synthesis method of polyaryletherketone grafted polyvinylpyrrolidone | 吉林大学 | 2020-04-21 | — | — | CN | claimed |
| CN-110229284-B | Synthesis method of polyaryletherketone grafted polyvinylpyrrolidone | 吉林大学 | 2020-04-21 | — | — | CN | disclosed |
| CN-110229284-B | Synthesis method of polyaryletherketone grafted polyvinylpyrrolidone | 吉林大学 | 2020-04-21 | — | — | CN | disclosed |
| CN-104513209-A | Water soluble triazine amino benzene sulfonic acid alkali metal salt derivative and preparation method and application thereof | UNIV EAST CHINA JIAOTONG | 2015-04-15 | — | — | CN | disclosed |
| EP-2268646-B9 | THIAZOLOPYRIDIN-2-YLOXY-PHENYL AND THIAZOLOPYRAZIN-2-YLOXY-PHENYL AMINES AS MODULATORS OF LEUKOTRIENE A4 HYDROLASE | JANSSEN PHARMACEUTICA NV (BE) | 2014-11-19 | — | — | EP | disclosed |
| US-8642788-B2 | Activators of executioner procaspases 3, 6 and 7 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-02-04 | — | — | US | disclosed |
| EP-2268646-B1 | THIAZOLOPYRIDIN-2-YLOXY-PHENYL AND THIAZOLOPYRAZIN-2-YLOXY-PHENYL AMINES AS MODULATORS OF LEUKOTRIENE A4 HYDROLASE | JANSSEN PHARMACEUTICA NV (BE) | 2013-10-02 | — | — | EP | disclosed |
| EP-2430019-B1 | COMPOUNDS WITH TWO FUSED BICYCLIC HETEROARYL MOIETIES AS MODULATORS OF LEUKOTRIENE A4 HYDROLASE | JANSSEN PHARMACEUTICA NV (BE) | 2013-09-18 | — | — | EP | disclosed |
| US-8399465-B2 | Compounds with two fused bicyclic heteroaryl moieties as modulators of leukotriene A4 hydrolase | JANSSEN PHARMACEUTICA NV (BE) | 2013-03-19 | — | — | US | disclosed |
| US-8357684-B2 | Thyazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amines as modulators of leukotriene A4 hydrolase | JANSSEN PHARMACEUTICA NV (BE) | 2013-01-22 | — | — | US | disclosed |
| WO-2009089508-A1 | ACTIVATORS OF EXECUTIONER PROCASPASES 3, 6 AND 7 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-07-16 | — | — | WO | disclosed |
| US-20090163693-A1 | Photoactive aromatic polymers and preparation methods thereof | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2009-06-25 | — | — | US | disclosed |
| WO-2008004751-A1 | AROMATIC POLYMERS HAVING OPTICAL ACTIVITY AND PREPARATION METHODS THEREOF | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2008-01-10 | — | — | WO | disclosed |
| EP-0527953-B1 | THERMALLY STABLE POLYVINYL CHLORIDE RESIN | GEON CO (US) | 1994-07-13 | — | — | EP | disclosed |
| US-5292823-A | Thermally stable polyvinyl chloride resin | THE GEON COMPANY (US) | 1994-03-08 | — | — | US | disclosed |
| EP-0527953-A1 | THERMALLY STABLE POLYVINYL CHLORIDE RESIN. | GOODRICH CO B F (US) | 1993-02-24 | — | — | EP | disclosed |
| WO-1991018028-A1 | THERMALLY STABLE POLYVINYL CHLORIDE RESIN | THE B.F. GOODRICH COMPANY (US) | 1991-11-28 | — | — | WO | disclosed |
| US-4902701-A | Tetrazolyl substituted tricyclic compounds and pharmacological compositions thereof | BURROUGHS WELCOME CO. (US) | 1990-02-20 | — | — | US | disclosed |
| EP-0093381-B1 | TRICYCLIC COMPOUNDS, PREPARATION, USE AND INTERMEDIATES | THE WELLCOME FOUNDATION LIMITED (GB) | 1986-07-23 | — | — | EP | disclosed |
| EP-0093381-A1 | Tricyclic compounds, preparation, use and intermediates | THE WELLCOME FOUNDATION LIMITED (GB) | 1983-11-09 | — | — | EP | disclosed |