Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1239675 | 0.78 | TDP1 (0.62) | TDP1ALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL1239670 | 0.78 | TDP1 (0.62) | TDP1ALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL16716192 | 0.76 | TDP1 (0.60) | TDP1ALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL1237353 | 0.76 | ALDH1A1 (0.61) | TDP1ALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL1237351 | 0.76 | ALDH1A1 (0.61) | TDP1ALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL3444977 | 0.76 | ALDH1A1 (0.61) | TDP1ALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL13108155 | 0.75 | TDP1 (0.48) | TDP1ALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL22649440 | 0.74 | ALDH1A1 (0.62) | TDP1ALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL11463490 | 0.74 | ALDH1A1 (0.62) | TDP1ALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL11480552 | 0.72 | ALDH1A1 (0.61) | TDP1ALDH1A1GAAPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0120728-A1 | Thiazine and thiazepine containing compounds | E.R. Squibb & Sons, Inc. (US) | 1984-10-03 | — | — | EP | disclosed |