Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 2/20 | 0.53 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | PPID | Q08752 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6600210 | 1.00 | ITGA4 (0.53) | ITGA4ITGB7MAPTTDP1MMP8 | |
| SCHEMBL7439390 | 1.00 | ITGA4 (0.53) | ITGA4ITGB7MAPTTDP1MMP8 | |
| SCHEMBL6428127 | 0.91 | ITGA4 (0.62) | ITGA4ITGB7MAPTTDP1CTSS | |
| SCHEMBL7428724 | 0.90 | ITGA4 (0.59) | ITGA4ITGB7MAPTTDP1MMP8 | |
| SCHEMBL7428720 | 0.90 | ITGA4 (0.59) | ITGA4ITGB7MAPTTDP1MMP8 | |
| SCHEMBL4022466 | 0.90 | ITGA4 (0.58) | ITGA4ITGB7MAPTTDP1CTSS | |
| SCHEMBL4022463 | 0.90 | ITGA4 (0.58) | ITGA4ITGB7MAPTTDP1CTSS | |
| SCHEMBL6440329 | 0.90 | ITGA4 (0.58) | ITGA4ITGB7MAPTTDP1CTSS | |
| SCHEMBL17287421 | 0.88 | PPID (0.54) | MMP8PPIDELANEMEN1KMT2A | |
| SCHEMBL3268059 | 0.87 | ACE (0.54) | ITGA4ITGB7MAPTTDP1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |