SCHEMBL7439501

SCHEMBL7439501

[CH2]CC(CCCCCCCC)OC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ZDHHC7 Q9NXF8 1/20 0.38
LMNA P02545 1/20 0.38
PRKD3 O94806 3/20 0.38
PRKCG P05129 3/20 0.38
PRKCB P05771 3/20 0.38
PRKCA P17252 3/20 0.38
PRKCH P24723 3/20 0.38
PRKCI P41743 3/20 0.38
PRKCE Q02156 3/20 0.38
PRKCQ Q04759 3/20 0.38
PRKCZ Q05513 3/20 0.38
PRKCD Q05655 3/20 0.38
PRKD1 Q15139 3/20 0.38
DNM1 Q05193 2/20 0.37
LPAR6 P43657 3/20 0.37
LPAR1 Q92633 3/20 0.37
LPAR4 Q99677 3/20 0.37
LPAR5 Q9H1C0 3/20 0.37
LPAR2 Q9HBW0 3/20 0.37
LPAR3 Q9UBY5 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4508770 1.00 ZDHHC7 (0.38) ZDHHC7LMNAPRKD3PRKCGPRKCB
SCHEMBL7194789 1.00 ZDHHC7 (0.38) ZDHHC7LMNAPRKD3PRKCGPRKCB
SCHEMBL8933419 1.00 ZDHHC7 (0.38) ZDHHC7LMNAPRKD3PRKCGPRKCB
SCHEMBL386111 1.00 ZDHHC7 (0.38) ZDHHC7LMNAPRKD3PRKCGPRKCB
SCHEMBL385374 0.98 OPRM1 (0.37) ZDHHC7LMNAPRKD3PRKCGPRKCB
SCHEMBL385914 0.91
SCHEMBL28571242 0.90 OPRM1 (0.34) ZDHHC7LMNAPRKD3PRKCGPRKCB
SCHEMBL17676329 0.85 TSHR (0.44) ZDHHC7LMNAPRKD3PRKCGPRKCB
SCHEMBL14520047 0.85 TSHR (0.44) ZDHHC7LMNAPRKD3PRKCGPRKCB
SCHEMBL18165672 0.85 TSHR (0.44) ZDHHC7LMNAPRKD3PRKCGPRKCB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0327263-B1 Hair growth stimulation with nitroxide and other radicals PROCTOR PETER H (US) 1994-09-07 EP disclosed
EP-0492930-A2 Transdermal delivery of dobutamine ELI LILLY AND COMPANY (US) 1992-07-01 EP disclosed
EP-0327263-A1 Hair growth stimulation with nitroxide and other radicals PROCTOR, Peter H. (US) 1989-08-09 EP disclosed
WO-1988005653-A1 TOPICAL COMPOSITION FOR STIMULATING HAIR GROWTH WITH STABLE FREE RADICALS PROCTOR PETER H (US) 1988-08-11 WO disclosed
US-4150114-A ENHANCED PENETRATION THE PROCTER & GAMBLE COMPANY (US) 1979-04-17 US disclosed
US-4148893-A SUGAR ESTER AND DIALKYL SULFOXIDE ENHANCE PENETRATION THROUGH SKIN THE PROCTER & GAMBLE COMPANY (US) 1979-04-10 US disclosed
US-4148874-A ENHANCE PENETRATION OF PHARMOCOLOGICALLY ACTIVE AGENTS THROUGH THE SKIN THE PROCTER & GAMBLE COMPANY (US) 1979-04-10 US disclosed
US-4148924-A Dermatological compositions THE PROCTER & GAMBLE COMPANY (US) 1979-04-10 US disclosed
US-4148917-A PENETRATION THE PROCTER & GAMBLE COMPANY (US) 1979-04-10 US disclosed
US-4148887-A SUGAR ESTER WITH A METHYL SULFOXIDE THE PROCTER & GAMBLE COMPANY (US) 1979-04-10 US disclosed
US-4130667-A A SUCROSE ESTER AND A PHOSPHINE OXIDE THE PROCTER & GAMBLE COMPANY (US) 1978-12-19 US disclosed
US-4130643-A STEROID, SUCROSE ESTER, SULFOXIDE THE PROCTER & GAMBLE COMPANY (US) 1978-12-19 US disclosed
US-4046886-A SUGAR ESTER, PHOSPHINE OXIDE THE PROCTER & GAMBLE COMPANY (US) 1977-09-06 US disclosed
US-3953599-A ANTICHOLINERGIC SCOPOLAMINE ESTERS THE PROCTER & GAMBLE COMPANY (US) 1976-04-27 US disclosed
US-3952099-A MICROBIOCIDE, SUGAR ESTER, SULFOXIDE THE PROCTER & GAMBLE COMPANY (US) 1976-04-20 US disclosed