Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.54 |
| ▸ | F2R | P25116 | 3/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7446606 | 0.87 | STS (0.42) | ITGB3ITGA2BCAPN1ALDH1A1NPC1 | |
| Hydrochloric Acid SCHEMBL7439581 | 0.85 | ITGB3 (0.54) | ITGB3ITGA2BF2RALDH1A1NPC1 | |
| Hydrochloric Acid SCHEMBL7439586 | 0.85 | ITGB3 (0.49) | ITGB3ITGA2BF2RALDH1A1NPC1 | |
| SCHEMBL7447082 | 0.85 | ITGB3 (0.48) | ITGB3ITGA2BF2RALDH1A1HTT | |
| SCHEMBL7451972 | 0.84 | ITGB3 (0.50) | ITGB3ITGA2BF2RALDH1A1HTT | |
| SCHEMBL7459730 | 0.84 | ITGB3 (0.47) | ITGB3ITGA2BF2RALDH1A1HTT | |
| SCHEMBL7445679 | 0.83 | ITGB3 (0.63) | ITGB3ITGA2BF2R | |
| Hydrochloric Acid SCHEMBL7445140 | 0.83 | ITGB3 (0.54) | ITGB3ITGA2BF2R | |
| Hydrochloric Acid SCHEMBL7448711 | 0.83 | ITGB3 (0.57) | ITGB3ITGA2BF2RCAPN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7448697 | 0.80 | ITGB3 (0.64) | ITGB3ITGA2BF2RALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384028-B1 | TREATMENT OF CARDIOVASCULAR DISORDERS, ANTICOAGULANTS AND VALVE REPLACEMENT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |
| WO-1996029309-A1 | N-ACYLPIPERIDINYLCARBONYLAMINOCARBOXYLIC ACIDS AND THEIR USE AS GLYCOPROTEIN IIB/IIa ANTAGONISTS AND FIBRINOGEN-BLOOD PLATELETS BINDING INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-09-26 | — | — | WO | disclosed |