Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 3/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 3/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10886471 | 0.87 | APP (0.51) | PDE4BAPPMAOBACHEMEN1 | |
| SCHEMBL10884505 | 0.82 | MAPT (0.47) | APPMAOBACHEMEN1KMT2A | |
| SCHEMBL7436927 | 0.81 | PDE7A (0.46) | MEN1KMT2AMAPK10ALDH1A1MAPT | |
| SCHEMBL7410880 | 0.81 | PDGFRB (0.49) | PDE4DPDE4BMEN1KMT2AMAPK10 | |
| SCHEMBL10887682 | 0.80 | CYP1A2 (0.47) | MEN1KMT2AMAPK10ALDH1A1MAPT | |
| SCHEMBL7431081 | 0.80 | MAPK10 (0.52) | PDE4BMEN1KMT2AMAPK10ALDH1A1 | |
| Girisopam SCHEMBL637118 | 0.80 | MAPK10 (0.62) | PDE4DMEN1KMT2AMAPK10ALDH1A1 | |
| SCHEMBL15985265 | 0.80 | MAPK10 (0.52) | MEN1KMT2AMAPK10ALDH1A1MAPT | |
| Girisopam SCHEMBL8350989 | 0.80 | MAPK10 (0.62) | PDE4DMEN1KMT2AMAPK10ALDH1A1 | |
| SCHEMBL7606361 | 0.80 | APP (0.43) | PDE4BAPPMAOBACHEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322346-A | 5H-2,3-Benzodiazepine derivatives | KOROSI JENO | 1982-03-30 | — | — | US | disclosed |