Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 2/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7605575 | 0.91 | CYP1A2 (0.43) | PDGFRBMAPK10CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7436927 | 0.87 | PDE7A (0.46) | PDGFRBMAPK10CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL15974264 | 0.86 | CHEK1 (0.51) | MAPK10CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7439770 | 0.86 | MAPT (0.47) | PDGFRBMAPK10CYP1A2CYP3A4CYP2C9 | |
| Nerisopam SCHEMBL1004757 | 0.86 | CYP1A2 (0.63) | MAPK10CYP1A2CYP3A4CYP2C9CYP2C19 | |
| Nerisopam SCHEMBL8349837 | 0.86 | CYP1A2 (0.63) | MAPK10CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7442033 | 0.86 | PKM (0.45) | PDGFRBCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7402865 | 0.86 | PDGFRB (0.49) | PDGFRBMAPK10CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6420733 | 0.86 | MEN1 (0.52) | MAPK10CYP1A2CYP3A4CYP2C9CYP2C19 | |
| Girisopam SCHEMBL637118 | 0.85 | MAPK10 (0.62) | PDGFRBMAPK10ALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002088096-A1 | COMPOUNDS INHIBITING CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, PREPARATION AND USES THEREOF | NEURO3D (FR) | 2002-11-07 | — | — | WO | disclosed |
| US-4322346-A | 5H-2,3-Benzodiazepine derivatives | KOROSI JENO | 1982-03-30 | — | — | US | disclosed |