Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 7/20 | 0.51 |
| ▸ | CACNA1D | Q01668 | 7/20 | 0.51 |
| ▸ | CACNA1S | Q13698 | 7/20 | 0.51 |
| ▸ | CACNA1C | Q13936 | 7/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370072 | 1.00 | CACNA1F (0.51) | CACNA1FCACNA1DCACNA1SCACNA1CCACNA1B | |
| SCHEMBL27404285 | 0.91 | CACNA1F (0.62) | CACNA1FCACNA1DCACNA1SCACNA1CCACNA1B | |
| SCHEMBL7374956 | 0.90 | CACNA1B (0.61) | CACNA1FCACNA1DCACNA1SCACNA1CCACNA1B | |
| SCHEMBL7329073 | 0.87 | CACNA1F (0.66) | CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7372306 | 0.84 | CACNA1C (0.49) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL7369783 | 0.84 | CACNA1C (0.49) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL7327248 | 0.83 | HIF1A (0.65) | CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7552226 | 0.81 | CYP2C9 (0.61) | CACNA1FCACNA1DCACNA1SCACNA1CCACNA1B | |
| SCHEMBL7446669 | 0.81 | CYP2C9 (0.61) | CACNA1FCACNA1DCACNA1SCACNA1CCACNA1B | |
| SCHEMBL7370944 | 0.81 | TBXA2R (0.51) | CACNA1FCACNA1DCACNA1SCACNA1CCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994002463-A1 | ANTIHYPERTENSIVE 1,4-DIHYDROPYRIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-02-03 | — | — | WO | disclosed |