Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16913325 | 0.92 | MAPK10 (0.50) | MAPTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL16913113 | 0.91 | CHEK1 (0.45) | MAPTALDH1A1MEN1KMT2ACYP1A2 | |
| Nerisopam SCHEMBL8349837 | 0.86 | CYP1A2 (0.63) | MAPTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL15974264 | 0.86 | CHEK1 (0.51) | MAPTALDH1A1MEN1KMT2ACYP1A2 | |
| Nerisopam SCHEMBL1004757 | 0.86 | CYP1A2 (0.63) | MAPTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL7410880 | 0.86 | PDGFRB (0.49) | MAPTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL6420733 | 0.86 | MEN1 (0.52) | MAPTALDH1A1MEN1KMT2ACYP1A2 | |
| Girisopam SCHEMBL8350989 | 0.86 | MAPK10 (0.62) | MAPTALDH1A1MEN1KMT2ALMNA | |
| Girisopam SCHEMBL637118 | 0.86 | MAPK10 (0.62) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL9429651 | 0.85 | MEN1 (0.46) | MAPTALDH1A1MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5288863-A | Cyclization; reacting hydrazine with an acetonyl-, chloro-, dimethoxybenzophenone | EGIS GYOGYSZERGYAR RT. (HU) | 1994-02-22 | — | — | US | disclosed |
| US-4322346-A | 5H-2,3-Benzodiazepine derivatives | KOROSI JENO | 1982-03-30 | — | — | US | disclosed |