Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24978408 | 0.83 | KMT2A (0.46) | TSHRSMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL23331000 | 0.80 | MEN1 (0.43) | TSHRSMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL23301458 | 0.77 | ABL1 (0.45) | SMN1; SMN2KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL23331087 | 0.71 | HDAC1 (0.47) | KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL24978407 | 0.70 | HDAC3 (0.43) | TSHRSMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL23330648 | 0.70 | HDAC3 (0.46) | TSHRSMN1; SMN2KMT2ARAB9ANPC1 | |
| SCHEMBL7437558 | 0.69 | GSK3B (0.44) | TSHRSMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL23330999 | 0.68 | HDAC3 (0.40) | TSHRSMN1; SMN2KMT2AMEN1PTPN1 | |
| SCHEMBL5650768 | 0.67 | SMN1; SMN2 (0.50) | TSHRSMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL12791628 | 0.67 | CETP (0.64) | TSHRSMN1; SMN2KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565566-A | N6-(ENDO(1R,2S,4S)-2-NORBORNYL)-9-METHYLADENINE OR N6-(ENDO(1S,2R,4R)-2-NORBORNYL)-9-METHYLADENINE | DISCOVERY THERAPEUTICS, INC. (US) | 1996-10-15 | — | — | US | disclosed |
| US-5256398-A | Mixture of adenosine, or an adenosine antagonist, with an adenosine receptor | WHITBY RESEARCH, INC. (US) | 1993-10-26 | — | — | US | disclosed |
| EP-0457773-A4 | N?6 -SUBSTITUTED 9-METHYLADENINES: A NEW CLASS OF ADENOSINE RECEPTOR ANTAGONISTS | — | 1993-03-10 | — | — | EP | disclosed |
| US-5117830-A | Dilating the vascular system with adenosine; labeling; supplying a adenosine recetor antagonist | WHITBY RESEARCH, INC. (US) | 1992-06-02 | — | — | US | disclosed |
| EP-0457773-A1 | N?6 -SUBSTITUTED 9-METHYLADENINES: A NEW CLASS OF ADENOSINE RECEPTOR ANTAGONISTS | WHITBY RESEARCH, Inc. (US) | 1991-11-27 | — | — | EP | disclosed |
| WO-1990009178-A1 | N6-SUBSTITUTED 9-METHYLADENINES: A NEW CLASS OF ADENOSINE RECEPTOR ANTAGONISTS | WHITBY RESEARCH, INC. (US) | 1990-08-23 | — | — | WO | disclosed |