Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.49 |
| ▸ | ITGAV | P06756 | 2/20 | 0.49 |
| ▸ | F7 | P08709 | 13/20 | 0.40 |
| ▸ | F3 | P13726 | 12/20 | 0.40 |
| ▸ | F2 | P00734 | 12/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440166 | 1.00 | ITGB3 (0.49) | ITGB3ITGA2BITGAVF7F3 | |
| SCHEMBL7438482 | 0.93 | ITGB3 (0.49) | ITGB3ITGA2BITGAVF7F3 | |
| SCHEMBL3894297 | 0.89 | ITGB3 (0.51) | ITGB3ITGA2BITGAVF2 | |
| SCHEMBL6702744 | 0.89 | ITGB3 (0.51) | ITGB3ITGA2BITGAVF2 | |
| Hydrochloric Acid SCHEMBL6703865 | 0.87 | ITGB3 (0.42) | ITGB3ITGA2BF7F3F2 | |
| Hydrochloric Acid SCHEMBL6703856 | 0.87 | ITGB3 (0.42) | ITGB3ITGA2BF7F3F2 | |
| SCHEMBL6701002 | 0.86 | ITGB3 (0.45) | ITGB3ITGA2BF7F3F2 | |
| SCHEMBL6701009 | 0.86 | ITGB3 (0.45) | ITGB3ITGA2BF7F3F2 | |
| SCHEMBL6702839 | 0.85 | ITGB3 (0.51) | ITGB3ITGA2BPRSS1 | |
| SCHEMBL6701882 | 0.84 | ITGB3 (0.39) | ITGB3ITGA2BF7F3F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6034238-A | ANTIINFLAMMATORY AGENTS; ANTIARTHRITIC AGENT | HOECHST MARION ROUSSEL DEUTSCHLAND GMBH (DE) | 2000-03-07 | — | — | US | disclosed |
| EP-0905139-A2 | 5 ring heterocyles, process for preparation, use as inhibitors of leukocyte adhesion and pharmaceutical preparations comprising them | Hoechst Marion Roussel Deutschland GmbH (DE) | 1999-03-31 | — | — | EP | disclosed |