Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 19/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7444024 | 0.99 | CASP1 (0.48) | CASP1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7435530 | 0.88 | CYP1A2 (0.63) | CASP1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7682326 | 0.88 | CNR2 (0.46) | CASP1 | |
| SCHEMBL7684457 | 0.87 | CASP1 (0.44) | CASP1 | |
| Hydrochloric Acid SCHEMBL7689742 | 0.87 | CNR2 (0.45) | CASP1 | |
| Hydrochloric Acid SCHEMBL7691000 | 0.86 | CASP1 (0.44) | CASP1 | |
| SCHEMBL7678294 | 0.86 | CASP1 (0.44) | CASP1 | |
| SCHEMBL7429152 | 0.86 | CYP1A2 (0.60) | CASP1CYP1A2CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL8171192 | 0.85 | CASP1 (0.44) | CASP1 | |
| SCHEMBL7431058 | 0.85 | SMN1; SMN2 (0.54) | CASP1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710153-A | INTERLEUKIN CONVERTING ENZYME INHIBITORS | ONO PHRAMACEUTICAL CO., LTD. (JP) | 1998-01-20 | — | — | US | claimed |
| EP-0761680-A2 | Tetrazole compounds having Interleukin-1beta converting enzyme inhibitory activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-03-12 | — | — | EP | claimed |