Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16839803 | 0.81 | PPID (0.44) | ALDH1A1LMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL1344175 | 0.79 | PPID (0.58) | ALDH1A1SMN1; SMN2LMNAMAPTGAA | |
| SCHEMBL30700389 | 0.78 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2LMNARAB9AMAPT | |
| SCHEMBL75805 | 0.78 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2LMNARAB9AMAPT | |
| Hydrochloric Acid SCHEMBL10886319 | 0.78 | PPID (0.57) | ALDH1A1SMN1; SMN2LMNAMAPTGAA | |
| SCHEMBL31215234 | 0.77 | PPID (0.64) | ALDH1A1SMN1; SMN2RAB9AKDM4EALOX15 | |
| SCHEMBL2039737 | 0.77 | PPID (0.64) | ALDH1A1SMN1; SMN2RAB9AKDM4EALOX15 | |
| SCHEMBL31215205 | 0.77 | MAPT (0.60) | ALDH1A1SMN1; SMN2LMNARAB9AMAPT | |
| Hydrochloric Acid SCHEMBL5434602 | 0.77 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2LMNARAB9AMAPT | |
| SCHEMBL7712013 | 0.77 | MAPT (0.60) | ALDH1A1SMN1; SMN2LMNARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |