SCHEMBL7440417

SCHEMBL7440417

Cc1cc2c(cc1N)CC(CCCCCC(=O)N1CCC[C@H]1C(=O)C1CCN[C@@H]1C(O)=S)C2

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 14/20 0.34
HTR7 P34969 14/20 0.34
DPP4 P27487 2/20 0.33
PREP P48147 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9048117 0.85 PREP (0.42) HTR1AHTR7DPP4PREP
SCHEMBL9049455 0.82 PREP (0.45) HTR1AHTR7DPP4PREP
SCHEMBL7303639 0.82 CPT2 (0.31)
SCHEMBL9050498 0.79 PREP (0.44) HTR1AHTR7DPP4PREP
SCHEMBL9049198 0.78 PREP (0.46) HTR1AHTR7DPP4PREP
SCHEMBL9050209 0.78 PREP (0.46) HTR1AHTR7DPP4PREP
SCHEMBL7434234 0.75 CPT2 (0.38) PREP
SCHEMBL9046377 0.75 PREP (0.47) DPP4PREP
SCHEMBL9050181 0.75 PREP (0.47) DPP4PREP
SCHEMBL8153384 0.73 PREP (0.56) PREP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0372484-B1 Condensed benzene derivative ZERIA PHARM CO LTD (JP) 1994-10-26 EP disclosed
US-5028604-A Cognition Activators ZERIA PHARMACEUTICAL CO., LTD. (JP) 1991-07-02 US disclosed