Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.67 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.62 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8811962 | 1.00 | ACHE (0.67) | ACHEEPHX2EPHX1 | |
| SCHEMBL10772425 | 0.98 | ACHE (0.64) | ACHEEPHX2 | |
| SCHEMBL7349927 | 0.95 | ACHE (0.70) | ACHEEPHX2EPHX1 | |
| SCHEMBL7351683 | 0.94 | ACHE (0.67) | ACHEEPHX2 | |
| SCHEMBL5703710 | 0.93 | ACHE (0.66) | ACHEEPHX2 | |
| SCHEMBL6539639 | 0.88 | ACHE (0.62) | ACHEEPHX2 | |
| SCHEMBL473236 | 0.88 | ACHE (0.85) | ACHEEPHX2EPHX1 | |
| SCHEMBL473096 | 0.88 | ACHE (0.85) | ACHEEPHX2EPHX1 | |
| SCHEMBL10447924 | 0.88 | ACHE (0.85) | ACHEEPHX2EPHX1 | |
| SCHEMBL7785857 | 0.88 | ACHE (0.85) | ACHEEPHX2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4288416-A2 | SMALL MOLECULE INHIBITORS OF GRP78 AND USES THEREOF | The Regents Of The University Of Michigan (US) | 2023-12-13 | — | — | EP | disclosed |
| WO-2022169834-A2 | SMALL MOLECULE INHIBITORS OF GRP78 AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2022-08-11 | — | — | WO | disclosed |
| EP-0900081-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2002-01-09 | — | — | EP | disclosed |
| EP-0900081-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997036591-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-10-09 | — | — | WO | disclosed |
| EP-0703905-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO. INC. (US) | 1996-04-03 | — | — | EP | disclosed |
| EP-0577775-A4 | ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES. | RHONE POULENC RORER INT (US) | 1995-01-11 | — | — | EP | disclosed |
| EP-0577775-A1 | ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1994-01-12 | — | — | EP | disclosed |
| WO-1992017196-A1 | ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-10-15 | — | — | WO | disclosed |