Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 7/20 | 0.41 |
| ▸ | FAP | Q12884 | 5/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1977433 | 0.96 | EPHX2 (0.59) | EPHX2NPSR1DPP4FAPDPP7 | |
| SCHEMBL2411177 | 0.94 | EPHX2 (0.62) | EPHX2NPSR1DPP4FAPDPP7 | |
| Hydrochloric Acid SCHEMBL6871695 | 0.94 | EPHX2 (0.58) | EPHX2NPSR1DPP4FAPDPP7 | |
| SCHEMBL18845118 | 0.94 | EPHX2 (0.62) | EPHX2NPSR1DPP4FAPDPP7 | |
| Hydrochloric Acid SCHEMBL75462 | 0.92 | EPHX2 (0.61) | EPHX2NPSR1DPP4FAPDPP7 | |
| SCHEMBL4450020 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL76321 | 0.89 | EPHX2 (0.47) | EPHX2DPP4DPP7KDM4ETET2 | |
| Hydrochloric Acid SCHEMBL7131992 | 0.88 | EPHX2 (0.57) | EPHX2NPSR1DPP4FAPDPP7 | |
| SCHEMBL23165799 | 0.83 | EPHX2 (0.43) | EPHX2DPP4DPP7KDM4EPOLB | |
| SCHEMBL23165798 | 0.83 | EPHX2 (0.43) | EPHX2DPP4DPP7KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |