SCHEMBL1977433

SCHEMBL1977433

COC(=O)CNC1CCCC1

nearest known ligand 0.59

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 4/20 0.59
NPSR1 Q6W5P4 1/20 0.46
KDM4E B2RXH2 2/20 0.43
POLB P06746 1/20 0.43
DPP4 P27487 8/20 0.41
DPP7 Q9UHL4 6/20 0.41
FAP Q12884 5/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
DPP8 Q6V1X1 1/20 0.40
DPP9 Q86TI2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6871695 0.98 EPHX2 (0.58) EPHX2NPSR1KDM4EPOLBDPP4
SCHEMBL18845118 0.98 EPHX2 (0.62) EPHX2NPSR1KDM4EPOLBDPP4
SCHEMBL2411177 0.98 EPHX2 (0.62) EPHX2NPSR1KDM4EPOLBDPP4
Hydrochloric Acid SCHEMBL75462 0.96 EPHX2 (0.61) EPHX2NPSR1KDM4EPOLBDPP4
SCHEMBL7440501 0.96 EPHX2 (0.55) EPHX2NPSR1KDM4EPOLBDPP4
Hydrochloric Acid SCHEMBL7131992 0.92 EPHX2 (0.57) EPHX2NPSR1KDM4EPOLBDPP4
SCHEMBL4450020 0.91
Hydrochloric Acid SCHEMBL76321 0.89 EPHX2 (0.47) EPHX2KDM4EDPP4DPP7MEN1
Hydrochloric Acid SCHEMBL7134822 0.86 EPHX2 (0.51) EPHX2NPSR1KDM4EPOLBDPP4
SCHEMBL23165798 0.83 EPHX2 (0.43) EPHX2KDM4EPOLBDPP4DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250235462-A1 NOVEL CAPSID ASSEMBLY INHIBITORS AM SCIENCES INC (KR) 2025-07-24 US disclosed
US-20250170121-A1 ISOQUINOLINONE COMPOUND, AND PREPARATION METHOD AND USE THEREFOR FUDAN UNIVERSITY (CN) 2025-05-29 US disclosed
EP-4416150-A1 NOVEL CAPSID ASSEMBLY INHIBITORS AM Sciences Inc (KR) 2024-08-21 EP disclosed
CN-118159540-A Novel capsid assembly inhibitor 南韩商AM科学股份有限公司 2024-06-07 CN disclosed
WO-2024009283-A1 AT2 ANTAGONISTS FOR NON-ADDICTIVE PAIN RELIEF UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2024-01-11 WO disclosed
CN-116693456-A Isoquinolinones compound, preparation method and application thereof 复旦大学 2023-09-05 CN disclosed
WO-2023160726-A1 ISOQUINOLINONE COMPOUND, AND PREPARATION METHOD AND USE THEREFOR 复旦大学 2023-08-31 WO disclosed
WO-2023063698-A1 NOVEL CAPSID ASSEMBLY INHIBITORS AM SCIENCES INC (KR) 2023-04-20 WO disclosed
US-8980903-B2 Fused pyridine, pyrimidine and triazine compounds as cell cycle inhibitors AMGEN INC. (US) 2015-03-17 US disclosed
US-8980903-B2 Fused pyridine, pyrimidine and triazine compounds as cell cycle inhibitors AMGEN INC. (US) 2015-03-17 US disclosed
CN-1212704-A Serine protease inhibitors AKZO NOBEL NV (NL) 1999-03-31 CN disclosed
EP-0886647-A1 SERINE PROTEASE INHIBITORS Akzo Nobel N.V. (NL) 1998-12-30 EP disclosed
CN-1202902-A Thrombin inhibitors AKZO NOBEL NV (NL) 1998-12-23 CN disclosed
WO-1998047876-A1 HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTITHROMBOTIC AGENTS AKZO NOBEL N.V. (NL) 1998-10-29 WO disclosed
EP-0858464-A1 THROMBIN INHIBITORS Akzo Nobel N.V. (NL) 1998-08-19 EP disclosed
WO-1997031937-A1 SERINE PROTEASE INHIBITORS AKZO NOBEL N.V. (NL) 1997-09-04 WO disclosed
WO-1997031939-A1 SERINE PROTEASE INHIBITORS AKZO NOBEL N.V. (NL) 1997-09-04 WO disclosed
WO-1997030073-A1 SERINE PROTEASE INHIBITORS AKZO NOBEL N.V. (NL) 1997-08-21 WO disclosed
WO-1997017363-A1 THROMBIN INHIBITORS AKZO NOBEL N.V. (NL) 1997-05-15 WO disclosed
EP-0640594-A1 Hydantoin derivative as metalloprotease inhibitor FUJIREBIO INC. (JP) 1995-03-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250235462-A1 NOVEL CAPSID ASSEMBLY INHIBITORS ZC3HAV1, GTF3C3, ZC3HAV1L EPHX2 4025/4885NPSR1 4367/4885KDM4E 1998/4885
US-20250170121-A1 ISOQUINOLINONE COMPOUND, AND PREPARATION METHOD AND USE THEREFOR FABP5, FABP4, FABP1 EPHX2 3520/4885NPSR1 3565/4885KDM4E 2494/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.