Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP3 | P08254 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KLK7 | P49862 | 1/20 | 0.50 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2467817 | 0.89 | FOLH1 (0.65) | FOLH1SIRT2SIRT1MAPTMMP9 | |
| SCHEMBL1491720 | 0.89 | FOLH1 (0.65) | FOLH1SIRT2SIRT1MAPTMMP9 | |
| SCHEMBL699636 | 0.89 | FOLH1 (0.65) | FOLH1SIRT2SIRT1MAPTMMP9 | |
| SCHEMBL5328146 | 0.88 | SIRT2 (0.66) | FOLH1SIRT2SIRT1MAPTKLK7 | |
| SCHEMBL5328141 | 0.88 | SIRT2 (0.66) | FOLH1SIRT2SIRT1MAPTKLK7 | |
| SCHEMBL29401894 | 0.87 | GGT1 (0.56) | CTSKFOLH1MAPTPAX8TDP1 | |
| SCHEMBL4958981 | 0.86 | SYK (0.60) | CTSKFOLH1SIRT2SIRT1MAPT | |
| SCHEMBL918813 | 0.86 | SYK (0.60) | CTSKFOLH1SIRT2SIRT1MAPT | |
| SCHEMBL1021938 | 0.86 | SYK (0.60) | CTSKFOLH1SIRT2SIRT1MAPT | |
| SCHEMBL17039826 | 0.85 | FOLH1 (0.60) | FOLH1SIRT2SIRT1MAPTKLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244836-B1 | TRIPEPTIDE DERIVATIVES | Dainippon Pharmaceutical Co., Ltd. (JP) | 1993-08-18 | — | — | EP | disclosed |