Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 0.73 |
| ▸ | ITGA2B | P08514 | 15/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7393434 | 0.94 | ITGB3 (0.65) | ITGB3ITGA2BNPC1RAB9ATP53 | |
| SCHEMBL7399438 | 0.84 | ITGB3 (1.00) | ITGB3ITGA2BITGAV | |
| SCHEMBL8233920 | 0.84 | ITGB3 (1.00) | ITGB3ITGA2BITGAV | |
| SCHEMBL7440690 | 0.84 | ITGB3 (1.00) | ITGB3ITGA2BITGAV | |
| SCHEMBL7393420 | 0.79 | ITGB3 (0.89) | ITGB3ITGA2B | |
| SCHEMBL7393424 | 0.79 | ITGB3 (0.89) | ITGB3ITGA2B | |
| SCHEMBL7437422 | 0.78 | ITGB3 (0.77) | ITGB3ITGA2BITGAV | |
| SCHEMBL7593932 | 0.77 | ITGB3 (0.52) | ITGB3ITGA2BMEN1KMT2ANPC1 | |
| SCHEMBL7593928 | 0.77 | ITGB3 (0.52) | ITGB3ITGA2BMEN1KMT2ANPC1 | |
| SCHEMBL7503387 | 0.75 | ITGB3 (0.50) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593603-B1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-11-20 | — | — | EP | disclosed |
| US-6127359-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2000-10-03 | — | — | US | disclosed |
| EP-0593603-A1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-04-27 | — | — | EP | disclosed |
| WO-1993000095-A2 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-07 | — | — | WO | disclosed |