Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7441224 | 0.85 | NPC1 (0.47) | TDP1MAPTCYP3A4HPGDKDM4E | |
| SCHEMBL3742612 | 0.82 | TDP1 (0.52) | TDP1MAPTCYP3A4KMT2AMAPK1 | |
| SCHEMBL4905808 | 0.79 | TDP1 (0.58) | TDP1MAPTCYP3A4KMT2AMAPK1 | |
| Methylamine SCHEMBL13837152 | 0.78 | MAPT (0.48) | TDP1MAPTCYP3A4KMT2AMAPK1 | |
| SCHEMBL19619388 | 0.78 | MAPT (0.52) | TDP1MAPTCYP3A4KMT2AMAPK1 | |
| SCHEMBL3754394 | 0.78 | MAPT (0.52) | TDP1MAPTCYP3A4KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL10431496 | 0.76 | MAPT (0.50) | TDP1MAPTCYP3A4KMT2AMAPK1 | |
| SCHEMBL10393811 | 0.76 | KMT2A (0.45) | TDP1MAPTCYP3A4KMT2AMAPK1 | |
| SCHEMBL379725 | 0.75 | KMT2A (0.54) | TDP1MAPTCYP3A4KMT2AMAPK1 | |
| SCHEMBL5964067 | 0.75 | GSK3B (0.56) | TDP1MAPTCYP3A4KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4281180-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediated therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1981-07-28 | — | — | US | claimed |