Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6956765 | 1.00 | EDNRA (0.80) | EDNRAEDNRB | |
| SCHEMBL7804146 | 0.93 | EDNRA (0.71) | EDNRAEDNRB | |
| SCHEMBL7813879 | 0.93 | EDNRA (0.81) | EDNRAEDNRB | |
| SCHEMBL6960208 | 0.93 | EDNRA (0.81) | EDNRAEDNRB | |
| SCHEMBL7437638 | 0.90 | EDNRA (0.67) | EDNRAEDNRB | |
| SCHEMBL7933827 | 0.90 | EDNRA (0.83) | EDNRAEDNRB | |
| Sb-209670 SCHEMBL29550762 | 0.89 | EDNRA (1.00) | EDNRAEDNRB | |
| Sb-209670 SCHEMBL4197810 | 0.89 | EDNRA (1.00) | EDNRAEDNRB | |
| Sb-209670 SCHEMBL1028671 | 0.89 | EDNRA (1.00) | EDNRAEDNRB | |
| Sb-209670 SCHEMBL8734573 | 0.89 | EDNRA (1.00) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612244-B1 | ENDOTHELIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2001-09-19 | — | — | EP | claimed |
| EP-0634175-B1 | Pharmaceutical combination, containing a renin-angiotensin-system inhibitor and an endothelin antagonist | HOFFMANN LA ROCHE (CH) | 2001-01-10 | — | — | EP | disclosed |