Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | IL1RN | P18510 | 3/20 | 0.51 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.51 |
| ▸ | LAP3 | P28838 | 2/20 | 0.49 |
| ▸ | ANPEP | P15144 | 1/20 | 0.49 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.49 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.49 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7431625 | 0.92 | MME (0.55) | MMEFOLH1LTA4HIL1RNERAP2 | |
| SCHEMBL7442518 | 0.90 | MME (0.51) | MMEFOLH1LTA4HIL1RNERAP2 | |
| SCHEMBL10509278 | 0.90 | FOLH1 (0.64) | MMEFOLH1LTA4HIL1RNERAP2 | |
| SCHEMBL29674545 | 0.90 | FOLH1 (0.64) | MMEFOLH1LTA4HIL1RNERAP2 | |
| SCHEMBL7431310 | 0.90 | MME (0.53) | MMEFOLH1LTA4HIL1RNERAP2 | |
| SCHEMBL10509294 | 0.90 | FOLH1 (0.64) | MMEFOLH1LTA4HIL1RNERAP2 | |
| SCHEMBL7431301 | 0.90 | MME (0.53) | MMEFOLH1LTA4HIL1RNERAP2 | |
| Ubenimex SCHEMBL5812930 | 0.90 | MME (0.66) | MMELTA4HLAP3ANPEPRNPEP | |
| Ubenimex SCHEMBL16782425 | 0.90 | MME (0.66) | MMELTA4HLAP3ANPEPRNPEP | |
| Ubenimex SCHEMBL8191715 | 0.90 | MME (0.66) | MMELTA4HLAP3ANPEPRNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4453003-A | ENZYME INHIBITORS, ANTIINFLAMMATORY AGENTS | UMEZAWA HAMAO (JP) | 1984-06-05 | — | — | US | disclosed |
| US-4391986-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediates therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-07-05 | — | — | US | disclosed |
| US-4281180-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediated therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1981-07-28 | — | — | US | disclosed |