⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1385 | 0.91 | — | — | |
| SCHEMBL29100923 | 0.86 | — | — | |
| Hydroxyl Radical SCHEMBL11648475 | 0.86 | — | — | |
| SCHEMBL11349480 | 0.86 | — | — | |
| Ammonia Solution, Strong SCHEMBL28309341 | 0.86 | — | — | |
| SCHEMBL1561 | 0.74 | — | — | |
| SCHEMBL2552774 | 0.74 | — | — | |
| SCHEMBL23921986 | 0.73 | — | — | |
| SCHEMBL2776967 | 0.72 | — | — | |
| SCHEMBL135172 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190040026-A1 | COMPOSITIONS AND METHODS OF TREATMENT WITH PRODRUGS OF TIZOXANIDE, AN ANALOGUE OR SALT THEREOF | ROMARK LABORATORIES, L.C. (US) | 2019-02-07 | — | — | US | disclosed |
| EP-3217795-A1 | COMPOSITIONS AND METHODS OF TREATMENT WITH PRODRUGS OF TIZOXANIDE, AN ANALOGUE OR SALT THEREOF | Romark Laboratories, L.C. (US) | 2017-09-20 | — | — | EP | disclosed |
| EP-3078377-A2 | NITAZOXANIDE AND TIZOXANIDE AS ANTI-VIRAL AGENTS | Romark Laboratories, L.C. (US) | 2016-10-12 | — | — | EP | disclosed |
| WO-2016077420-A1 | COMPOSITIONS AND METHODS OF TREATMENT WITH PRODRUGS OF TIZOXANIDE, AN ANALOGUE OR SALT THEREOF | ROMARK LABORATORIES, L.C. (US) | 2016-05-19 | — | — | WO | disclosed |
| EP-2429986-A1 | HALOALKYL HETEROARYL BENZAMIDE COMPOUNDS | Romark Laboratories, L.C. (US) | 2012-03-21 | — | — | EP | disclosed |
| US-7839569-B2 | Polarizing plate and liquid crystal display | FUJIFILM CORPORATION (JP) | 2010-11-23 | — | — | US | disclosed |
| WO-2010132404-A1 | HALOALKYL HETEROARYL BENZAMIDE COMPOUNDS | ROMARK LABORATORIES L.C. (US) | 2010-11-18 | — | — | WO | disclosed |
| US-20070258141-A1 | Polarizing Plate and Liquid Crystal Display | FUJIFILM CORPORATION (JP) | 2007-11-08 | — | — | US | disclosed |