Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 19/20 | 0.62 |
| ▸ | MMP13 | P45452 | 15/20 | 0.62 |
| ▸ | MMP2 | P08253 | 11/20 | 0.62 |
| ▸ | MMP3 | P08254 | 11/20 | 0.62 |
| ▸ | ADAM17 | P78536 | 11/20 | 0.62 |
| ▸ | MMP9 | P14780 | 9/20 | 0.62 |
| ▸ | MMP7 | P09237 | 8/20 | 0.62 |
| ▸ | MMP8 | P22894 | 5/20 | 0.62 |
| ▸ | MMP14 | P50281 | 2/20 | 0.62 |
| ▸ | ADAM10 | O14672 | 2/20 | 0.46 |
| ▸ | ADAM9 | Q13443 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6768683 | 1.00 | MMP1 (0.62) | MMP1MMP13MMP2MMP3ADAM17 | |
| SCHEMBL6768692 | 0.90 | MMP1 (0.62) | MMP1MMP13MMP2MMP3ADAM17 | |
| SCHEMBL6775791 | 0.88 | MMP1 (0.55) | MMP1MMP13MMP2MMP3ADAM17 | |
| SCHEMBL6765881 | 0.88 | MMP1 (0.55) | MMP1MMP13MMP2MMP3ADAM17 | |
| SCHEMBL6775313 | 0.88 | MMP1 (0.55) | MMP1MMP13MMP2MMP3ADAM17 | |
| SCHEMBL6765885 | 0.88 | MMP1 (0.55) | MMP1MMP13MMP2MMP3ADAM17 | |
| SCHEMBL6775798 | 0.88 | MMP1 (0.55) | MMP1MMP13MMP2MMP3ADAM17 | |
| SCHEMBL6775320 | 0.88 | MMP1 (0.55) | MMP1MMP13MMP2MMP3ADAM17 | |
| SCHEMBL6766152 | 0.88 | MMP1 (0.60) | MMP1MMP13MMP2MMP3ADAM17 | |
| SCHEMBL6766147 | 0.88 | MMP1 (0.60) | MMP1MMP13MMP2MMP3ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1233016-A1 | Biphenyl sulfonamides useful as matrix metalloproteinase inhibitors | WARNER-LAMBERT COMPANY (US) | 2002-08-21 | — | — | EP | disclosed |