Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 20/20 | 0.66 |
| ▸ | CTRC | Q99895 | 6/20 | 0.66 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.63 |
| ▸ | F10 | P00742 | 3/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7445929 | 0.89 | F2 (0.60) | F2CTRCPRSS2F10 | |
| SCHEMBL6553019 | 0.88 | F2 (0.73) | F2CTRCPRSS2F10 | |
| SCHEMBL7602897 | 0.79 | F2 (0.73) | F2CTRCPRSS2F10 | |
| SCHEMBL7451490 | 0.78 | F2 (0.70) | F2CTRCPRSS2F10 | |
| Hydrochloric Acid SCHEMBL7451487 | 0.77 | F2 (0.69) | F2CTRCPRSS2F10 | |
| SCHEMBL7440084 | 0.77 | F2 (1.00) | F2CTRCPRSS2F10 | |
| SCHEMBL7602926 | 0.77 | F2 (0.73) | F2CTRCPRSS2F10 | |
| Hydrochloric Acid SCHEMBL6553152 | 0.76 | F2 (0.98) | F2CTRCPRSS2F10 | |
| SCHEMBL7446067 | 0.76 | F2 (1.00) | F2CTRCPRSS2F10 | |
| SCHEMBL7451365 | 0.76 | F2 (0.67) | F2CTRCPRSS2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859607-B1 | GUANIDINO PROTEASE INHIBITORS | DIMENSIONAL PHARM INC (US) | 2002-12-18 | — | — | EP | disclosed |
| EP-0859607-A4 | GUANIDINO PROTEASE INHIBITORS | DIMENSIONAL PHARM INC (US) | 1999-05-06 | — | — | EP | disclosed |
| EP-0859607-A1 | GUANIDINO PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1998-08-26 | — | — | EP | disclosed |
| US-5792769-A | POTENT ANTICOAGULANT, ANTIINFLAMMATORY AGENT; TREATMENT/PROPHYLAXIS OF RESPIRATORY SYSTEM DISORDERS, VASCULAR SYSTEM DISORDERS, ANTITUMOR AGENTS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1998-08-11 | — | — | US | disclosed |
| WO-1997011693-A1 | GUANIDINO PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1997-04-03 | — | — | WO | disclosed |