Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.47 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | RRM1 | P23921 | 1/20 | 0.41 |
| ▸ | NPY4R | P50391 | 9/20 | 0.39 |
| ▸ | NPY1R | P25929 | 5/20 | 0.39 |
| ▸ | NPY2R | P49146 | 4/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | OTC | P00480 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25328211 | 1.00 | DPP7 (0.47) | DPP7GNAI3GNAO1GNAI1RRM1 | |
| SCHEMBL23626315 | 0.88 | DPP7 (0.61) | DPP7GNAI3GNAO1GNAI1RRM1 | |
| SCHEMBL23610947 | 0.88 | DPP7 (0.61) | DPP7GNAI3GNAO1GNAI1RRM1 | |
| SCHEMBL10559478 | 0.85 | DPP7 (0.45) | DPP7GNAI3GNAO1GNAI1RRM1 | |
| SCHEMBL27944509 | 0.85 | DPP7 (0.45) | DPP7GNAI3GNAO1GNAI1RRM1 | |
| SCHEMBL4798434 | 0.83 | DPP7 (0.47) | DPP7GNAI3GNAO1GNAI1RRM1 | |
| SCHEMBL7327484 | 0.83 | DPP7 (0.53) | DPP7GNAI3GNAO1GNAI1RRM1 | |
| SCHEMBL13062154 | 0.83 | DPP7 (0.56) | DPP7GNAI3GNAO1GNAI1RRM1 | |
| SCHEMBL2304732 | 0.83 | DPP7 (0.56) | DPP7GNAI3GNAO1GNAI1RRM1 | |
| SCHEMBL17301799 | 0.83 | DPP7 (0.53) | DPP7GNAI3GNAO1GNAI1RRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063819-A | PROTECTING NEURONS FROM DAMAGE BY ADMINISTERING TO HUMANS POLYGUADINO COMPOUNDS | CYPROS PHARMACEUTICAL CORP. (US) | 2000-05-16 | — | — | US | disclosed |
| WO-1998036743-A1 | NEUROPROTECTIVE POLY-GUANIDINO COMPOUNDS WHICH BLOCK PRESYNAPTIC N AND P/Q CALCIUM CHANNELS | CYPROS PHARMACEUTICAL CORPORATION (US) | 1998-08-27 | — | — | WO | disclosed |