Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.56 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.49 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.49 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.49 |
| ▸ | RRM1 | P23921 | 1/20 | 0.47 |
| ▸ | NPY4R | P50391 | 9/20 | 0.42 |
| ▸ | NPY1R | P25929 | 5/20 | 0.42 |
| ▸ | NPY2R | P49146 | 4/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | OTC | P00480 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13062154 | 1.00 | DPP7 (0.56) | DPP7GNAI3GNAO1GNAI1RRM1 | |
| Hydrochloric Acid SCHEMBL9556550 | 0.98 | DPP7 (0.54) | DPP7GNAI3GNAO1GNAI1RRM1 | |
| Hydrochloric Acid SCHEMBL9556545 | 0.98 | DPP7 (0.54) | DPP7GNAI3GNAO1GNAI1RRM1 | |
| SCHEMBL7324660 | 0.89 | DPP7 (0.68) | DPP7GNAI3GNAO1GNAI1RRM1 | |
| SCHEMBL7324651 | 0.89 | DPP7 (0.68) | DPP7GNAI3GNAO1GNAI1RRM1 | |
| SCHEMBL19371883 | 0.89 | DPP7 (0.63) | DPP7GNAI3GNAO1GNAI1RRM1 | |
| SCHEMBL23610947 | 0.88 | DPP7 (0.61) | DPP7GNAI3GNAO1GNAI1RRM1 | |
| SCHEMBL23626315 | 0.88 | DPP7 (0.61) | DPP7GNAI3GNAO1GNAI1RRM1 | |
| SCHEMBL27114206 | 0.87 | DPP7 (0.76) | DPP7GNAI3GNAO1GNAI1RRM1 | |
| SCHEMBL24420660 | 0.86 | DPP7 (0.73) | DPP7GNAI3GNAO1GNAI1RRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022225422-A1 | HEPTAPEPTIDE AMIDES FOR USE IN THE TREATMENT OF HMGB1-DEPENDENT DISEASES | Federal State Budgetary Institution Scientific center of biomedical technologies of Federal Medical and Biological Agency (RU) | 2022-10-27 | — | — | WO | disclosed |
| EP-2349242-B1 | AMINO ACID SALTS OF PROSTAGLANDINS | NOVAER HOLDINGS INC (US) | 2018-12-05 | — | — | EP | disclosed |
| US-8722739-B2 | Amino acid salts of prostaglandins | NOVAER HOLDINGS, INC. (US) | 2014-05-13 | — | — | US | disclosed |
| US-20140031423-A1 | AMINO ACID SALTS OF PROSTAGLANDINS | NOVAER HOLDINGS, INC. (US) | 2014-01-30 | — | — | US | disclosed |
| US-8623918-B2 | Amino acid salts of prostaglandins | NOVAER HOLDINGS, INC. (US) | 2014-01-07 | — | — | US | disclosed |
| US-8470882-B2 | — | — | 2013-06-25 | — | — | US | disclosed |
| EP-2349242-A2 | AMINO ACID SALTS OF PROSTAGLANDINS | Aerie Pharmaceuticals, Inc. (US) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010096123-A2 | AMINO ACID SALTS OF PROSTAGLANDINS | AERIE PHARMACEUTICALS, INC. (US) | 2010-08-26 | — | — | WO | disclosed |
| US-20100105771-A1 | AMINO ACID SALTS OF PROSTAGLANDINS | NOVAER HOLDINGS, INC. | 2010-04-29 | — | — | US | disclosed |
| US-20100105775-A1 | AMINO ACID SALTS OF PROSTAGLANDINS | NOVAER HOLDINGS, INC. | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105771-A1 | AMINO ACID SALTS OF PROSTAGLANDINS | PTGIS, PTGES, PTGIR | DPP7 1412/4885GNAI3 1385/4885GNAO1 2388/4885 |
| US-20100105775-A1 | AMINO ACID SALTS OF PROSTAGLANDINS | PTGIS, PTGES, PTGIR | DPP7 1412/4885GNAI3 1385/4885GNAO1 2388/4885 |
| US-20140031423-A1 | AMINO ACID SALTS OF PROSTAGLANDINS | PTGIS, PTGES, PTGIR | DPP7 1412/4885GNAI3 1385/4885GNAO1 2388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.