Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.60 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.60 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.60 |
| ▸ | CPA1 | P15085 | 4/20 | 0.56 |
| ▸ | CPA3 | P15088 | 3/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.56 |
| ▸ | CPB1 | P15086 | 1/20 | 0.56 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.56 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.55 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.54 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442261 | 1.00 | CYP1A2 (0.63) | CYP1A2SLC1A3SLC1A2SLC1A1CPA1 | |
| SCHEMBL21811160 | 0.87 | CYP1A2 (0.59) | CYP1A2SLC1A3SLC1A2SLC1A1CPA1 | |
| SCHEMBL7431758 | 0.86 | CYP1A2 (0.68) | CYP1A2SLC1A3SLC1A2SLC1A1CPA1 | |
| SCHEMBL7441570 | 0.86 | CYP1A2 (0.68) | CYP1A2SLC1A3SLC1A2SLC1A1CPA1 | |
| Potassium Ion SCHEMBL9622154 | 0.85 | CYP1A2 (0.49) | CYP1A2SLC1A3SLC1A2SLC1A1CPA1 | |
| Potassium Ion SCHEMBL9622463 | 0.85 | CYP1A2 (0.49) | CYP1A2SLC1A3SLC1A2SLC1A1CPA1 | |
| SCHEMBL7432418 | 0.85 | CYP1A2 (0.86) | CYP1A2SLC1A3SLC1A2SLC1A1CPA1 | |
| SCHEMBL9622038 | 0.85 | CYP1A2 (0.86) | CYP1A2SLC1A3SLC1A2SLC1A1CPA1 | |
| SCHEMBL7439697 | 0.85 | CYP1A2 (0.86) | CYP1A2SLC1A3SLC1A2SLC1A1CPA1 | |
| SCHEMBL9622141 | 0.85 | CYP1A2 (0.61) | CYP1A2SLC1A3SLC1A2SLC1A1CPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166212-A | Hypotensive agents, analgesics | CIBA-GEIGY CORPORATION (US) | 1992-11-24 | — | — | US | disclosed |
| US-5096925-A | N-substituted butyramide derivatives | CIBA-GEIGY CORPORATION (US) | 1992-03-17 | — | — | US | disclosed |
| US-5021430-A | Enkephalinase inhibitors, analgesics, hypotensives | CIBA-GEIGY CORPORATION (US) | 1991-06-04 | — | — | US | disclosed |
| US-4939261-A | ANALGESICS, ANTIDEPRESSANTS, HYPOTENSIVE AGENTS, NEUROLEPTIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1990-07-03 | — | — | US | disclosed |
| EP-0185079-A1 | — | CIBA GEIGY AG | 1986-06-25 | — | — | EP | disclosed |
| WO-1986000066-A1 | N-SUBSTITUTED BUTYRAMIDE DERIVATIVES | CIBA-GEIGY AG (CH) | 1986-01-03 | — | — | WO | disclosed |