Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31358286 | 0.79 | GAA (0.50) | GAAMGAMSIMGAM2CA12 | |
| SCHEMBL22556589 | 0.78 | HMGCR (0.38) | GAACYP2C19HDAC6HDAC1HDAC2 | |
| SCHEMBL17480043 | 0.77 | HDAC6 (0.37) | NFKB1NFKB2RELACA12CA1 | |
| SCHEMBL5001089 | 0.75 | CA12 (0.55) | GAAMGAMSIMGAM2NFKB1 | |
| SCHEMBL13690856 | 0.74 | HDAC6 (0.37) | NFKB1NFKB2RELACA12CA1 | |
| SCHEMBL18758783 | 0.73 | CA12 (0.43) | GAAMGAMSIMGAM2NFKB1 | |
| SCHEMBL499027 | 0.72 | SMN1; SMN2 (0.40) | GAAMGAMSIMGAM2NFKB1 | |
| SCHEMBL31358486 | 0.72 | GAA (0.47) | GAAMGAMSIMGAM2CA12 | |
| SCHEMBL24737134 | 0.72 | NFKB1 (0.45) | GAAMGAMSIMGAM2NFKB1 | |
| SCHEMBL13690848 | 0.72 | HDAC6 (0.36) | HDAC6HDAC1HDAC2CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |