Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL743938 | 0.92 | LTA4H (0.84) | LTA4HKCNH2 | |
| SCHEMBL745947 | 0.91 | LTA4H (0.81) | LTA4HKCNH2 | |
| SCHEMBL745918 | 0.91 | LTA4H (0.81) | LTA4HKCNH2 | |
| SCHEMBL745294 | 0.91 | LTA4H (0.82) | LTA4HKCNH2 | |
| Hydrochloric Acid SCHEMBL3744812 | 0.91 | LTA4H (0.79) | LTA4HKCNH2 | |
| SCHEMBL743540 | 0.90 | LTA4H (0.98) | LTA4HKCNH2 | |
| SCHEMBL743430 | 0.90 | LTA4H (0.79) | LTA4HKCNH2 | |
| SCHEMBL744978 | 0.90 | LTA4H (0.78) | LTA4HKCNH2 | |
| SCHEMBL745349 | 0.89 | LTA4H (1.00) | LTA4H | |
| SCHEMBL745562 | 0.89 | LTA4H (0.77) | LTA4HKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430019-A1 | COMPOUNDS WITH TWO FUSED BICYCLIC HETEROARYL MOIETIES AS MODULATORS OF LEUKOTRIENE A4 HYDROLASE | Janssen Pharmaceutica, N.V. (BE) | 2012-03-21 | — | — | EP | claimed |
| WO-2010132599-A1 | COMPOUNDS WITH TWO FUSED BICYCLIC HETEROARYL MOIETIES AS MODULATORS OF LEUKOTRIENE A4 HYDROLASE | JANSSEN PHARMACEUTICA NV (BE) | 2010-11-18 | — | — | WO | claimed |