Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3745097 | 0.84 | LTA4H (0.61) | LTA4H | |
| SCHEMBL744910 | 0.82 | LTA4H (0.83) | LTA4H | |
| Hydrochloric Acid SCHEMBL3744826 | 0.81 | LTA4H (0.82) | LTA4H | |
| SCHEMBL744597 | 0.80 | LTA4H (0.71) | LTA4H | |
| SCHEMBL3748603 | 0.80 | LTA4H (0.71) | LTA4H | |
| SCHEMBL3477170 | 0.80 | LTA4H (0.71) | LTA4H | |
| SCHEMBL3742258 | 0.80 | LTA4H (0.67) | LTA4H | |
| SCHEMBL744517 | 0.79 | LTA4H (0.84) | LTA4H | |
| Hydrochloric Acid SCHEMBL3753853 | 0.79 | LTA4H (0.70) | LTA4H | |
| Hydrochloric Acid SCHEMBL742243 | 0.79 | LTA4H (0.70) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430019-A1 | COMPOUNDS WITH TWO FUSED BICYCLIC HETEROARYL MOIETIES AS MODULATORS OF LEUKOTRIENE A4 HYDROLASE | Janssen Pharmaceutica, N.V. (BE) | 2012-03-21 | — | — | EP | claimed |
| WO-2010132599-A1 | COMPOUNDS WITH TWO FUSED BICYCLIC HETEROARYL MOIETIES AS MODULATORS OF LEUKOTRIENE A4 HYDROLASE | JANSSEN PHARMACEUTICA NV (BE) | 2010-11-18 | — | — | WO | claimed |