Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.31 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7446015 | 0.84 | TSHR (0.39) | AGTR1AGTR2 | |
| SCHEMBL7449121 | 0.83 | AGTR1 (0.30) | AGTR1AGTR2 | |
| SCHEMBL7429051 | 0.83 | AGTR1 (0.34) | AGTR1AGTR2 | |
| SCHEMBL7442286 | 0.83 | SMN1; SMN2 (0.39) | AGTR1AGTR2 | |
| SCHEMBL7439909 | 0.82 | MAP2K1 (0.34) | MAP2K1AGTR1 | |
| SCHEMBL7440753 | 0.82 | AGTR1 (0.30) | AGTR1AGTR2 | |
| SCHEMBL7442728 | 0.82 | AGTR1 (0.30) | AGTR1AGTR2 | |
| SCHEMBL7445818 | 0.82 | AGTR1 (0.31) | AGTR1AGTR2 | |
| SCHEMBL7433640 | 0.81 | AGTR1 (0.31) | AGTR1AGTR2 | |
| SCHEMBL7446270 | 0.81 | BRD4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0628559-B1 | Pyrimidine compounds and their use as pharmaceuticals | BEIERSDORF LILLY GMBH (DE) | 2002-04-03 | — | — | EP | disclosed |
| US-5602136-A | Pyrimidine compounds and their use as pharmaceuticals | BEIERSDORF-LILLY GMBH (DE) | 1997-02-11 | — | — | US | disclosed |
| US-5602137-A | Pyrimidine compounds and their use as pharmaceuticals | BEIERSDORF-LILLY GMBH (DE) | 1997-02-11 | — | — | US | disclosed |
| US-5571813-A | Fused pyrimidine compounds and their use as pharmaceuticals | BEIERSDORF-LILLY GMBH (DE) | 1996-11-05 | — | — | US | disclosed |
| EP-0628559-A1 | Pyrimidine compounds and their use as pharmaceuticals | Beiersdorf-Lilly GmbH (DE) | 1994-12-14 | — | — | EP | disclosed |