⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11124755 | 0.75 | CSNK2A1 (0.33) | — | |
| SCHEMBL11195709 | 0.73 | L3MBTL1 (0.36) | — | |
| SCHEMBL11191275 | 0.73 | PDE4A (0.30) | — | |
| SCHEMBL256090 | 0.73 | — | — | |
| SCHEMBL11041845 | 0.72 | — | — | |
| SCHEMBL4361443 | 0.71 | — | — | |
| SCHEMBL1005836 | 0.71 | — | — | |
| SCHEMBL12844533 | 0.71 | — | — | |
| SCHEMBL1509606 | 0.71 | — | — | |
| SCHEMBL9435912 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0397365-B1 | Arylthiazolylimidazoles as 5HT3 Antagonists | PFIZER (US) | 1994-03-02 | — | — | EP | disclosed |
| EP-0397365-A1 | Arylthiazolylimidazoles as 5HT3 Antagonists | PFIZER INC. (US) | 1990-11-14 | — | — | EP | disclosed |
| US-4914207-A | ANTIEMETICS | PFIZER INC. (US) | 1990-04-03 | — | — | US | disclosed |