Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 8/20 | 0.47 |
| ▸ | GCGR | P47871 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7299006 | 0.85 | ELANE (0.56) | ELANEGCGR | |
| SCHEMBL6266596 | 0.78 | ELANE (0.49) | ELANEALDH1A1MAPTHTT | |
| SCHEMBL6266593 | 0.78 | ELANE (0.49) | ELANEALDH1A1MAPTHTT | |
| SCHEMBL7301033 | 0.76 | ELANE (0.59) | ELANE | |
| SCHEMBL7301626 | 0.76 | ELANE (0.68) | ELANEMAPT | |
| SCHEMBL6261618 | 0.74 | ELANE (0.49) | ELANEL3MBTL1ALDH1A1MAPTHTT | |
| SCHEMBL6261622 | 0.74 | ELANE (0.49) | ELANEL3MBTL1ALDH1A1MAPTHTT | |
| SCHEMBL7301747 | 0.74 | ELANE (0.49) | ELANEALDH1A1MAPTHTTPRMT5 | |
| SCHEMBL7300428 | 0.73 | ELANE (0.59) | ELANEL3MBTL1 | |
| SCHEMBL7300078 | 0.71 | ELANE (0.52) | ELANEALDH1A1HTTPRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430025-A | Elastase-inhibiting peptides bearing a C-terminal trifluoromethylketone moiety | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-07-04 | — | — | US | disclosed |
| US-5296591-A | Enzyme inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0494071-A2 | Trifluoromethylketone tripeptide derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-08 | — | — | EP | disclosed |